standaard archief
Most comprehensive global study shows wide variation in cancer survival 12-01-2015 The most comprehensive international comparison of cancer survival to date (CONCORD-2 study), covering countries that are home to two-thirds of the world's population, shows extremely wide differences in survival between countries. The study, published in The Lancet, is based on data from nearly 26 million patients (including 75.000 children) from 279 cancer registries in 67 countries between 1995... Read further 
Increasing breast-conserving surgery for invasive breast cancer 12-01-2015 The amount of breast-conserving surgery in patients with invasive ductal breast cancer or invasive lobular breast cancer has risen in the Netherlands between 1990 and 2010. This increase is less pronounced in patients with invasive lobular tumor. According to a study by drs. W. Truin and colleagues these women are more likely to have a mastectomy compared with patients with invasive ductal breast ... Read further 
50% ovarian cancer patients have neuropathic symptoms after chemotherapy 12-01-2015 Slightly more than half of all women (51%) treated with chemotherapy for ovarian cancer suffer from neuropathic symptoms such as numbness and tingling in hands and feet. These symptoms can persist for at least 12 years after the end of treatment. In an article published in Gynecologic Oncology, IKNL-researcher Nicole Ezendam and colleagues show that these symptoms seriously affect the quality of l... Read further 
International consensus on definitions recurrences breast cancer studies 12-01-2015 A team of international breast cancer research experts has reached consensus on event definitions for classification of recurrence in breast cancer research. Martine Moosdorff (School for Oncology and Developmental Biology, Maastricht University) and colleagues (including IKNL researcher dr. Adri Voogd) recently published this study in the British Journal of Surgery. It is expected that these defi... Read further 
Detailed definitions of endpoints in breast cancer studies needed 12-01-2015 The variety of endpoints in scientific studies on breast cancer is so large and diverse that comparability is hampered and the risk of erroneous conclusions increases. Drs. Martine Moossdorff and colleagues therefore argue in a publication in the British Journal of Surgery to include more detailed descriptions of endpoints in order to promote transparency and comparability of these studies. Read further 
No change in node positivity rate despite increased lymph node yield 12-01-2015 In the evaluation of quality of care for patients with colon cancer, the number of lymph nodes evaluated has become a surrogate marker for surgical and pathological excellence. Despite the attention for lymph node yield, the association with nodal positivity rate has not often been articulated. Felice van Erning (IKNL) and colleagues show that the number of lymph nodes evaluated has increased from... Read further 
Role of ultrasound-guided lymph node biopsy in invasive breast cancer 12-01-2015 Patients with breast cancer whose positive axillary nodes were found after an ultrasound, have unfavorable disease characteristics and a worse prognosis than patients whose positive axillary nodes are detected after a sentinel node procedure. According to Nicole C. Verheuvel and colleagues the omission of lymph node dissection should therefore only be used in patients with a positive sentinel node... Read further 
Improved survival with adjuvant chemoradiation after gastric resection 10-11-2014 Patients with stomach cancer undergoing adjuvant chemoradiotherapy after a R1-resection have a better chance to survive than patients who were given no additional therapy after surgery. Research by JurriŽn Stiekema (NKI-AVL) and colleagues shows that adjuvant chemoradiotherapy is an independent prognostic factor for increasing overall survival of these patients. The results of this study were rece... Read further 
Improved survival of stage IV NSCLC due to increased use of chemo 10-11-2014 Due to increased use of chemotherapy in patients with stage IV non-small cell lung cancer (NSCLC), i.e. from 30% in 2001 to 48% in 2012, median survival improved with 3 weeks to 21 weeks in 2010-2012. Several meta-analyses have shown that chemotherapy in addition to best supportive care improves survival in this group of patients, but limited data were available on the use and effects in clinical ... Read further 
More attention needed for individual patient information 10-11-2014 The provision of information to patients with cancer is not optimal. The reason may be that the information provided by doctors and other caregivers is not adapted to the mental health status of cancer patients or that the information is 'insufficient' for the patient. This may result in anxious and depressive symptoms and complaints by patients, according to research of Nienke Beekers (IKNL) and ... Read further 
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